Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases

Many disease-susceptible SNPs exhibit significant disparity in ancestral and derived allele frequencies across worldwide populations. While previous studies have examined population differentiation of alleles at specific SNPs, global ethnic patterns of ensembles of disease risk alleles across human...

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Detalles Bibliográficos
Autores principales: Chen, Rong, Corona, Erik, Sikora, Martin, Dudley, Joel T., Morgan, Alex A., Moreno-Estrada, Andres, Nilsen, Geoffrey B., Ruau, David, Lincoln, Stephen E., Bustamante, Carlos D., Butte, Atul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325177/
https://www.ncbi.nlm.nih.gov/pubmed/22511877
http://dx.doi.org/10.1371/journal.pgen.1002621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325177/
https://www.ncbi.nlm.nih.gov/pubmed/22511877
http://dx.doi.org/10.1371/journal.pgen.1002621

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