Evolution of the Multi-Domain Structures of Virulence Genes in the Human Malaria Parasite, Plasmodium falciparum

The var gene family of Plasmodium falciparum encodes the immunodominant variant surface antigens PfEMP1. These highly polymorphic proteins are important virulence factors that mediate cytoadhesion to a variety of host tissues, causing sequestration of parasitized red blood cells in vital organs, inc...

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Detalles Bibliográficos
Autores principales: Buckee, Caroline O., Recker, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325180/
https://www.ncbi.nlm.nih.gov/pubmed/22511852
http://dx.doi.org/10.1371/journal.pcbi.1002451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325180/
https://www.ncbi.nlm.nih.gov/pubmed/22511852
http://dx.doi.org/10.1371/journal.pcbi.1002451

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