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Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium

The mechanisms of hypoxic injury to the developing human brain are poorly understood, despite being a major cause of chronic neurodevelopmental impairments. Recent work in the invertebrate Caenorhabditis elegans has shown that hypoxia causes discrete axon pathfinding errors in certain interneurons a...

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Detalles Bibliográficos
Autores principales: Stevenson, Tamara J., Trinh, Tony, Kogelschatz, Cory, Fujimoto, Esther, Lush, Mark E., Piotrowski, Tatjana, Brimley, Cameron J., Bonkowsky, Joshua L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325188/
https://www.ncbi.nlm.nih.gov/pubmed/22511881
http://dx.doi.org/10.1371/journal.pgen.1002638