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Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor

Autozygosity occurs when two chromosomal segments that are identical from a common ancestor are inherited from each parent. This occurs at high rates in the offspring of mates who are closely related (inbreeding), but also occurs at lower levels among the offspring of distantly related mates. Here,...

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Detalles Bibliográficos
Autores principales: Keller, Matthew C., Simonson, Matthew A., Ripke, Stephan, Neale, Ben M., Gejman, Pablo V., Howrigan, Daniel P., Lee, Sang Hong, Lencz, Todd, Levinson, Douglas F., Sullivan, Patrick F., The Schizophrenia Psychiatric Genome-Wide Association Study Consortium
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325203/
https://www.ncbi.nlm.nih.gov/pubmed/22511889
http://dx.doi.org/10.1371/journal.pgen.1002656