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Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor
Autozygosity occurs when two chromosomal segments that are identical from a common ancestor are inherited from each parent. This occurs at high rates in the offspring of mates who are closely related (inbreeding), but also occurs at lower levels among the offspring of distantly related mates. Here,...
Autores principales: | Keller, Matthew C., Simonson, Matthew A., Ripke, Stephan, Neale, Ben M., Gejman, Pablo V., Howrigan, Daniel P., Lee, Sang Hong, Lencz, Todd, Levinson, Douglas F., Sullivan, Patrick F., The Schizophrenia Psychiatric Genome-Wide Association Study Consortium |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325203/ https://www.ncbi.nlm.nih.gov/pubmed/22511889 http://dx.doi.org/10.1371/journal.pgen.1002656 |
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