Cargando…

Context-Dependent Dual Role of SKI8 Homologs in mRNA Synthesis and Turnover

Eukaryotic mRNA transcription and turnover is controlled by an enzymatic machinery that includes RNA polymerase II and the 3′ to 5′ exosome. The activity of these protein complexes is modulated by additional factors, such as the nuclear RNA polymerase II-associated factor 1 (Paf1c) and the cytoplasm...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorcey, Eavan, Rodriguez-Villalon, Antia, Salinas, Paula, Santuari, Luca, Pradervand, Sylvain, Harshman, Keith, Hardtke, Christian S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325215/
https://www.ncbi.nlm.nih.gov/pubmed/22511887
http://dx.doi.org/10.1371/journal.pgen.1002652