Human Monoclonal Antibodies to a Novel Cluster of Conformational Epitopes on HCV E2 with Resistance to Neutralization Escape in a Genotype 2a Isolate

The majority of broadly neutralizing antibodies to hepatitis C virus (HCV) are against conformational epitopes on the E2 glycoprotein. Many of them recognize overlapping epitopes in a cluster, designated as antigenic domain B, that contains residues G530 and D535. To gain information on other region...

Descripción completa

Detalles Bibliográficos
Autores principales: Keck, Zhen-yong, Xia, Jinming, Wang, Yong, Wang, Wenyan, Krey, Thomas, Prentoe, Jannick, Carlsen, Thomas, Li, Angela Ying-Jian, Patel, Arvind H., Lemon, Stanley M., Bukh, Jens, Rey, Felix A., Foung, Steven K. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325216/
https://www.ncbi.nlm.nih.gov/pubmed/22511875
http://dx.doi.org/10.1371/journal.ppat.1002653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325216/
https://www.ncbi.nlm.nih.gov/pubmed/22511875
http://dx.doi.org/10.1371/journal.ppat.1002653

Ejemplares similares