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A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study

INTRODUCTION: Circulating cell-free DNA (cf-DNA) is a useful indicator of cell death, and it can also be used to predict outcomes in various clinical disorders. Several innate immune mechanisms are known to be involved in eliminating DNA and chromatin-related material as part of the inhibition of po...

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Detalles Bibliográficos
Autores principales: Jylhävä, Juulia, Lyytikäinen, Leo-Pekka, Kähönen, Mika, Hutri-Kähönen, Nina, Kettunen, Johannes, Viikari, Jorma, Raitakari, Olli T., Lehtimäki, Terho, Hurme, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325226/
https://www.ncbi.nlm.nih.gov/pubmed/22511988
http://dx.doi.org/10.1371/journal.pone.0035426