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A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study
INTRODUCTION: Circulating cell-free DNA (cf-DNA) is a useful indicator of cell death, and it can also be used to predict outcomes in various clinical disorders. Several innate immune mechanisms are known to be involved in eliminating DNA and chromatin-related material as part of the inhibition of po...
Autores principales: | Jylhävä, Juulia, Lyytikäinen, Leo-Pekka, Kähönen, Mika, Hutri-Kähönen, Nina, Kettunen, Johannes, Viikari, Jorma, Raitakari, Olli T., Lehtimäki, Terho, Hurme, Mikko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325226/ https://www.ncbi.nlm.nih.gov/pubmed/22511988 http://dx.doi.org/10.1371/journal.pone.0035426 |
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