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Delayed Toxicity Associated with Soluble Anthrax Toxin Receptor Decoy-Ig Fusion Protein Treatment

Soluble receptor decoy inhibitors, including receptor-immunogloubulin (Ig) fusion proteins, have shown promise as candidate anthrax toxin therapeutics. These agents act by binding to the receptor-interaction site on the protective antigen (PA) toxin subunit, thereby blocking toxin binding to cell su...

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Detalles Bibliográficos
Autores principales: Thomas, Diane, Naughton, John, Cote, Christopher, Welkos, Susan, Manchester, Marianne, Young, John A. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325282/
https://www.ncbi.nlm.nih.gov/pubmed/22511955
http://dx.doi.org/10.1371/journal.pone.0034611