Cargando…

Delayed Toxicity Associated with Soluble Anthrax Toxin Receptor Decoy-Ig Fusion Protein Treatment

Soluble receptor decoy inhibitors, including receptor-immunogloubulin (Ig) fusion proteins, have shown promise as candidate anthrax toxin therapeutics. These agents act by binding to the receptor-interaction site on the protective antigen (PA) toxin subunit, thereby blocking toxin binding to cell su...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thomas, Diane, Naughton, John, Cote, Christopher, Welkos, Susan, Manchester, Marianne, Young, John A. T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325282/ https://www.ncbi.nlm.nih.gov/pubmed/22511955 http://dx.doi.org/10.1371/journal.pone.0034611

Ejemplares similares

Anthrax Toxins in Context of Bacillus anthracis Spores and Spore Germination
por: Cote, Christopher K., et al.
Publicado: (2015)

Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo
por: Scobie, Heather M, et al.
Publicado: (2006)

Correction: Anthrax Toxin Receptor 2–Dependent Lethal Toxin Killing In Vivo
por: Scobie, Heather M, et al.
Publicado: (2008)

Tumor Endothelium Marker-8 Based Decoys Exhibit Superiority over Capillary Morphogenesis Protein-2 Based Decoys as Anthrax Toxin Inhibitors
por: Cai, Chenguang, et al.
Publicado: (2011)

Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana
por: Karuppanan, Kalimuthu, et al.
Publicado: (2017)

Changing the Receptor Specificity of Anthrax Toxin
por: Mechaly, Adva, et al.
Publicado: (2012)

Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation
por: Sun, Jianjun, et al.
Publicado: (2016)

Effects of N-Glycosylation on the Structure, Function, and Stability of a Plant-Made Fc-Fusion Anthrax Decoy Protein
por: Xiong, Yongao, et al.
Publicado: (2019)

Anthrax toxin takes charge
por: Dove, Alan W.
Publicado: (2003)

Anthrax toxin rafts into cells
por: Kurzchalia, Teymuras
Publicado: (2003)

The Ins and Outs of Anthrax Toxin
por: Friebe, Sarah, et al.
Publicado: (2016)

Anthrax Toxin Receptor 2 Determinants that Dictate the pH Threshold of Toxin Pore Formation
por: Scobie, Heather M., et al.
Publicado: (2007)

Anthrax Toxin-Expressing Bacillus cereus Isolated from an Anthrax-Like Eschar
por: Marston, Chung K., et al.
Publicado: (2016)

The Receptors that Mediate the Direct Lethality of Anthrax Toxin
por: Liu, Shihui, et al.
Publicado: (2012)

Converging physiological roles of the anthrax toxin receptors
por: Sergeeva, Oksana A., et al.
Publicado: (2019)

A Receptor-based Switch that Regulates Anthrax Toxin Pore Formation
por: Pilpa, Rosemarie M., et al.
Publicado: (2011)

A Viral Nanoparticle with Dual Function as an Anthrax Antitoxin and Vaccine
por: Manayani, Darly J, et al.
Publicado: (2007)

Cytolethal distending toxin B as a cell-killing component of tumor-targeted anthrax toxin fusion proteins
por: Bachran, C, et al.
Publicado: (2014)

An anthrax toxin variant with an improved activity in tumor targeting
por: Wein, Alexander N., et al.
Publicado: (2015)

Reductive Methylation and Mutation of an Anthrax Toxin Fusion Protein Modulates its Stability and Cytotoxicity
por: Bachran, Christopher, et al.
Publicado: (2014)

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis
por: Abrami, Laurence, et al.
Publicado: (2006)

Cytoskeleton as an Emerging Target of Anthrax Toxins
por: Trescos, Yannick, et al.
Publicado: (2012)

Atomic structure of anthrax PA pore elucidates toxin translocation
por: Jiang, Jiansen, et al.
Publicado: (2015)

Quantitative anti-PA IgG ELISA; assessment and comparability with the anthrax toxin neutralization assay in goats
por: Ndumnego, Okechukwu C, et al.
Publicado: (2013)

Targeting Anthrax Toxin Receptor 2 Ameliorates Endometriosis Progression
por: Lin, Shih-Chieh, et al.
Publicado: (2019)

Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera
por: Das, Soumita, et al.
Publicado: (2018)

Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer
por: Myung, Jae-Kyung, et al.
Publicado: (2017)

The anthrax toxin channel: a barrel of LFs
por: Blaustein, Robert O.
Publicado: (2011)

Suppressive Effects of Anthrax Lethal Toxin on Megakaryopoiesis
por: Chen, Po-Kong, et al.
Publicado: (2013)

Tumor Targeting and Drug Delivery by Anthrax Toxin
por: Bachran, Christopher, et al.
Publicado: (2016)

Treatment of ovarian cancer with modified anthrax toxin
por: Aktories, Klaus
Publicado: (2022)

Evidence for a Proton–Protein Symport Mechanism in the Anthrax Toxin Channel
por: Basilio, Daniel, et al.
Publicado: (2009)

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections
por: Alameh, Saleem, et al.
Publicado: (2020)

Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling
por: Paccani, Silvia Rossi, et al.
Publicado: (2005)

Latest therapeutic target for gastric cancer: Anthrax toxin receptor 1
por: Sun, Ke-Ran, et al.
Publicado: (2021)

Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
por: Choate, Lauren A., et al.
Publicado: (2021)

Anthrax Toxin Receptor 2 is expressed in murine and tumor vasculature and functions in endothelial proliferation and morphogenesis
por: Reeves, Claire V., et al.
Publicado: (2009)

The Effects of Anthrax Lethal Toxin on Host Barrier Function
por: Xie, Tao, et al.
Publicado: (2011)

Disulfide Bonds in the Ectodomain of Anthrax Toxin Receptor 2 Are Required for the Receptor-Bound Protective-Antigen Pore to Function
por: Sun, Jianjun, et al.
Publicado: (2010)

Functions of Phenylalanine Residues within the β-Barrel Stem of the Anthrax Toxin Pore
por: Wang, Jie, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_pmq43ovc6l4gak0ci6v2epgtq6