Discovery of Regulatory Elements in Human ATP-Binding Cassette Transporters through Expression Quantitative Trait Mapping

ATP-Binding Cassette (ABC) membrane transporters determine the disposition of many drugs, metabolites and endogenous compounds. Coding region variation in ABC transporters is the cause of many genetic disorders, but much less is known about the genetic basis and functional outcome of ABC transporter...

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Detalles Bibliográficos
Autores principales: Matsson, Pär, Yee, Sook Wah, Markova, Svetlana, Morrissey, Kari, Jenkins, Gerard, Xuan, Jiekun, Jorgenson, Eric, Kroetz, Deanna L., Giacomini, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325368/
https://www.ncbi.nlm.nih.gov/pubmed/21383772
http://dx.doi.org/10.1038/tpj.2011.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325368/
https://www.ncbi.nlm.nih.gov/pubmed/21383772
http://dx.doi.org/10.1038/tpj.2011.8

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