Cargando…

Discovery of Regulatory Elements in Human ATP-Binding Cassette Transporters through Expression Quantitative Trait Mapping

ATP-Binding Cassette (ABC) membrane transporters determine the disposition of many drugs, metabolites and endogenous compounds. Coding region variation in ABC transporters is the cause of many genetic disorders, but much less is known about the genetic basis and functional outcome of ABC transporter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsson, Pär, Yee, Sook Wah, Markova, Svetlana, Morrissey, Kari, Jenkins, Gerard, Xuan, Jiekun, Jorgenson, Eric, Kroetz, Deanna L., Giacomini, Kathleen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325368/ https://www.ncbi.nlm.nih.gov/pubmed/21383772 http://dx.doi.org/10.1038/tpj.2011.8

Ejemplares similares

New and Emerging Research on Solute Carrier and ATP Binding Cassette Transporters in Drug Discovery and Development: Outlook From the International Transporter Consortium
por: Giacomini, Kathleen M., et al.
Publicado: (2022)

Pharmacogene regulatory elements: from discovery to applications
por: Smith, Robin P, et al.
Publicado: (2012)

High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3
por: Chen, Eugene C., et al.
Publicado: (2022)

Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug–Drug Interaction and Associated Biomarker Levels in Healthy Volunteers
por: Yee, Sook Wah, et al.
Publicado: (2019)

Biophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins
por: Molinski, Steven V., et al.
Publicado: (2017)

ATP-Binding Cassette Systems of Brucella
por: Jenner, Dominic C., et al.
Publicado: (2009)

Selective substrate uptake: The role of ATP-binding cassette (ABC) importers in pathogenesis
por: Tanaka, Kari J., et al.
Publicado: (2017)

Human ATP-binding cassette (ABC) transporter family
por: Vasiliou, Vasilis, et al.
Publicado: (2009)

ATP-Binding Cassette Transporters in the Clinical Implementation of Pharmacogenetics
por: López-Fernández, Luis A.
Publicado: (2018)

The impact of ATP-binding cassette transporters on metabolic diseases
por: Ye, Zixiang, et al.
Publicado: (2020)

Multidrug resistance-associated protein 4 is a determinant of arsenite resistance
por: Yuan, Bo, et al.
Publicado: (2016)

Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements
por: Smith, Robin P., et al.
Publicado: (2014)

ATP-binding cassette systems in Burkholderia pseudomallei and Burkholderia mallei
por: Harland, David N, et al.
Publicado: (2007)

ATP-binding cassette (ABC) transporters in normal and pathological lung
por: van der Deen, Margaretha, et al.
Publicado: (2005)

Membrane Porters of ATP-Binding Cassette Transport Systems Are Polyphyletic
por: Wang, Bin, et al.
Publicado: (2009)

Expression pattern of human ATP-binding cassette transporters in skin
por: Takenaka, Saya, et al.
Publicado: (2013)

Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters
por: Zheng, Wei Hao, et al.
Publicado: (2013)

Ribosome protection by antibiotic resistance ATP-binding cassette protein
por: Su, Weixin, et al.
Publicado: (2018)

ABCMdb reloaded: updates on mutations in ATP binding cassette proteins
por: Tordai, Hedvig, et al.
Publicado: (2017)

Identification and Characterization of ATP-Binding Cassette Transporters in Chlamydomonas reinhardtii
por: Li, Xiangyu, et al.
Publicado: (2022)

The Role of ATP-Binding Cassette Proteins in Stem Cell Pluripotency
por: Saini, Prince, et al.
Publicado: (2023)

Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression and Promoter Activity Predict Variation
por: Hesselson, Stephanie E., et al.
Publicado: (2009)

Tracing the structural evolution of eukaryotic ATP binding cassette transporter superfamily
por: Xiong, Jie, et al.
Publicado: (2015)

Structural Features of the ATP-Binding Cassette (ABC) Transporter ABCA3
por: Paolini, Alessandro, et al.
Publicado: (2015)

Expression of some ATP-binding cassette transporters in acute myeloid leukemia
por: Salvia, Antonella Maria, et al.
Publicado: (2017)

Genome-wide analysis of ATP binding cassette (ABC) transporters in tomato
por: Ofori, Peter Amoako, et al.
Publicado: (2018)

Predictive Structure and Topology of Peroxisomal ATP-Binding Cassette (ABC) Transporters
por: Andreoletti, Pierre, et al.
Publicado: (2017)

Predicting ATP-Binding Cassette Transporters Using the Random Forest Method
por: Hou, Ruiyan, et al.
Publicado: (2020)

ATP-binding cassette transporters mediate differential biosynthesis of glycosphingolipid species
por: Budani, Monique, et al.
Publicado: (2021)

The Function and Expression of ATP-Binding Cassette Transporters Proteins in the Alzheimer's Disease
por: Aykac, Asli, et al.
Publicado: (2021)

The role of ATP-binding cassette subfamily A in the etiology of Alzheimer’s disease
por: Bossaerts, Liene, et al.
Publicado: (2022)

ATP-binding cassette transporters as possible targets for the intervention of neurodegenerative diseases
por: Lok, Hiu Chuen, et al.
Publicado: (2023)

The Role of ATP-Binding Cassette Transporters in Neuro-Inflammation: Relevance for Bioactive Lipids
por: Kooij, Gijs, et al.
Publicado: (2012)

A-Subclass ATP-Binding Cassette Proteins in Brain Lipid Homeostasis and Neurodegeneration
por: Piehler, Armin P., et al.
Publicado: (2012)

The ATP-Binding Cassette Proteins of the Deep-Branching Protozoan Parasite Trichomonas vaginalis
por: Kay, Christopher, et al.
Publicado: (2012)

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity
por: Rijpma, Sanna R, et al.
Publicado: (2014)

The pharmacological impact of ATP-binding cassette drug transporters on vemurafenib-based therapy
por: Wu, Chung-Pu, et al.
Publicado: (2014)

The ATP binding cassette transporter, ABCG1, localizes to cortical actin filaments
por: Pandzic, Elvis, et al.
Publicado: (2017)

ATP binding cassette and cholecystokinin A receptor genetic variations in gallstone susceptibility
por: Milanizadeh, Saman, et al.
Publicado: (2017)

The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease
por: Jacobo-Albavera, Leonor, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8in8bqf8t1n5d2g4dmj4ps5cab