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DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

MicroRNAs (miRNAs) are recognized as being central players in many biological processes and cellular pathways. Their roles in disease have been highlighted first by observation of their aberrant expression profiles in human tumors, and then by in vitro and in vivo functional studies in transformed c...

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Detalles Bibliográficos
Autores principales: Lopez-Serra, P, Esteller, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325426/
https://www.ncbi.nlm.nih.gov/pubmed/21860412
http://dx.doi.org/10.1038/onc.2011.354