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Insulin Glargine: A Reevaluation of Rodent Carcinogenicity Findings

The 1995 to 1997 lifetime carcinogenicity studies of insulin glargine in rats and mice were reanalyzed and reassessed for their validity according to current guidelines. In 2-year studies, 50 animals per sex and per group were used. Survival rates between weeks 80 and 90 in female mice and rats were...

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Detalles Bibliográficos
Autores principales: Stammberger, Ingo, Essermeant, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325594/
https://www.ncbi.nlm.nih.gov/pubmed/22215409
http://dx.doi.org/10.1177/1091581811431111