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Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer

The Kruppel-like factor (KLF) proteins are multitasked transcriptional regulators with an expanding tumor suppressor function. KLF2 is one of the prominent members of the family because of its diminished expression in malignancies and its growth-inhibitory, pro-apoptotic and anti-angiogenic roles. I...

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Detalles Bibliográficos
Autores principales: Taniguchi, H, Jacinto, F V, Villanueva, A, Fernandez, A F, Yamamoto, H, Carmona, F J, Puertas, S, Marquez, V E, Shinomura, Y, Imai, K, Esteller, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325596/
https://www.ncbi.nlm.nih.gov/pubmed/21892211
http://dx.doi.org/10.1038/onc.2011.387