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MutS homologue hMSH5: role in cisplatin-induced DNA damage response

BACKGROUND: Cisplatin (cis-diamminedichloroplatinum (II), CDDP) and its analogues constitute an important class of anticancer drugs in the treatment of various malignancies; however, its effectiveness is frequently affected by mutations in genes involved in the repair and signaling of cisplatin-indu...

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Detalles Bibliográficos
Autores principales: Tompkins, Joshua D, Wu, Xiling, Her, Chengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325843/
https://www.ncbi.nlm.nih.gov/pubmed/22401567
http://dx.doi.org/10.1186/1476-4598-11-10