Cargando…
MutS homologue hMSH5: role in cisplatin-induced DNA damage response
BACKGROUND: Cisplatin (cis-diamminedichloroplatinum (II), CDDP) and its analogues constitute an important class of anticancer drugs in the treatment of various malignancies; however, its effectiveness is frequently affected by mutations in genes involved in the repair and signaling of cisplatin-indu...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325843/ https://www.ncbi.nlm.nih.gov/pubmed/22401567 http://dx.doi.org/10.1186/1476-4598-11-10 |