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c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis

BACKGROUND: The c-Myb transcription factor is essential for the maintenance of stem-progenitor cells in bone marrow, colon epithelia, and neurogenic niches. c-Myb malfunction contributes to several types of malignancies including breast cancer. However, the function of c-Myb in the metastatic spread...

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Detalles Bibliográficos
Autores principales: Knopfová, Lucia, Beneš, Petr, Pekarčíková, Lucie, Hermanová, Markéta, Masařík, Michal, Pernicová, Zuzana, Souček, Karel, Šmarda, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325857/
https://www.ncbi.nlm.nih.gov/pubmed/22439866
http://dx.doi.org/10.1186/1476-4598-11-15