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Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells

BACKGROUND: HuR, an RNA binding protein involved in the post-transcriptional regulation of a wide spectrum of mRNAs, has been demonstrated to be a determinant of carcinogenesis and tumor aggressiveness in several cancer types. In this study, we investigated the role of HuR in the apoptosis and in th...

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Detalles Bibliográficos
Autores principales: Latorre, Elisa, Tebaldi, Toma, Viero, Gabriella, Spartà, Antonino Maria, Quattrone, Alessandro, Provenzani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325864/
https://www.ncbi.nlm.nih.gov/pubmed/22436134
http://dx.doi.org/10.1186/1476-4598-11-13