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Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells
BACKGROUND: Various by-products of the cellular metabolism, such as reactive carbonyl species (RCS) are potentially harmful to cells and tissues, and play a role in many physiological and pathological processes. Among various RCS is the highly reactive dicarbonyl glyoxal (GO), which is a natural phy...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325881/ https://www.ncbi.nlm.nih.gov/pubmed/22424056 http://dx.doi.org/10.1186/1752-153X-6-18 |