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Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells

BACKGROUND: Various by-products of the cellular metabolism, such as reactive carbonyl species (RCS) are potentially harmful to cells and tissues, and play a role in many physiological and pathological processes. Among various RCS is the highly reactive dicarbonyl glyoxal (GO), which is a natural phy...

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Detalles Bibliográficos
Autores principales: Larsen, Simon Asbjørn, Kassem, Moustapha, Rattan, Suresh IS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325881/
https://www.ncbi.nlm.nih.gov/pubmed/22424056
http://dx.doi.org/10.1186/1752-153X-6-18