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Therapeutic targeting of Krüppel-like factor 4 abrogates microglial activation
BACKGROUND: Neuroinflammation occurs as a result of microglial activation in response to invading micro-organisms or other inflammatory stimuli within the central nervous system. According to our earlier findings, Krüppel-like factor 4 (Klf4), a zinc finger transcription factor, is involved in micro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325890/ https://www.ncbi.nlm.nih.gov/pubmed/22429472 http://dx.doi.org/10.1186/1742-2094-9-57 |