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Therapeutic targeting of Krüppel-like factor 4 abrogates microglial activation

BACKGROUND: Neuroinflammation occurs as a result of microglial activation in response to invading micro-organisms or other inflammatory stimuli within the central nervous system. According to our earlier findings, Krüppel-like factor 4 (Klf4), a zinc finger transcription factor, is involved in micro...

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Detalles Bibliográficos
Autores principales: Kaushik, Deepak Kumar, Mukhopadhyay, Rupanjan, Kumawat, Kanhaiya Lal, Gupta, Malvika, Basu, Anirban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325890/
https://www.ncbi.nlm.nih.gov/pubmed/22429472
http://dx.doi.org/10.1186/1742-2094-9-57