Cargando…

Therapeutic targeting of Krüppel-like factor 4 abrogates microglial activation

BACKGROUND: Neuroinflammation occurs as a result of microglial activation in response to invading micro-organisms or other inflammatory stimuli within the central nervous system. According to our earlier findings, Krüppel-like factor 4 (Klf4), a zinc finger transcription factor, is involved in micro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaushik, Deepak Kumar, Mukhopadhyay, Rupanjan, Kumawat, Kanhaiya Lal, Gupta, Malvika, Basu, Anirban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325890/ https://www.ncbi.nlm.nih.gov/pubmed/22429472 http://dx.doi.org/10.1186/1742-2094-9-57

Ejemplares similares

Krüppel-like factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation
por: Kaushik, Deepak K, et al.
Publicado: (2010)

NLRP3 Inflammasome: Key Mediator of Neuroinflammation in Murine Japanese Encephalitis
por: Kaushik, Deepak Kumar, et al.
Publicado: (2012)

Abrogated Inflammatory Response Promotes Neurogenesis in a Murine Model of Japanese Encephalitis
por: Das, Sulagna, et al.
Publicado: (2011)

A Common Carcinogen Benzo[a]pyrene Causes Neuronal Death in Mouse via Microglial Activation
por: Dutta, Kallol, et al.
Publicado: (2010)

miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells
por: Sharma, Nikhil, et al.
Publicado: (2015)

Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells
por: Manocha, Gunjan Dhawan, et al.
Publicado: (2014)

Fenofibrate Reduces Mortality and Precludes Neurological Deficits in Survivors in Murine Model of Japanese Encephalitis Viral Infection
por: Sehgal, Neha, et al.
Publicado: (2012)

STING Mediates Neuronal Innate Immune Response Following Japanese Encephalitis Virus Infection
por: Nazmi, Arshed, et al.
Publicado: (2012)

Krüppel-like Factor 15: A Potential Therapeutic Target For Kidney Disease
por: Wang, Lefeng, et al.
Publicado: (2019)

Japanese Encephalitis Virus exploits the microRNA-432 to regulate the expression of Suppressor of Cytokine Signaling (SOCS) 5
por: Sharma, Nikhil, et al.
Publicado: (2016)

Krüppel-like factors in tumors: Key regulators and therapeutic avenues
por: Zhang, Yuchen, et al.
Publicado: (2023)

Krüppel-Like Factors in Vascular Inflammation: Mechanistic Insights and Therapeutic Potential
por: Sweet, David R., et al.
Publicado: (2018)

The Krüppel-like factor 2 and Krüppel-like factor 4 genes interact to maintain endothelial integrity in mouse embryonic vasculogenesis
por: Chiplunkar, Aditi R, et al.
Publicado: (2013)

Participation of Krüppel-like Factors in Atherogenesis
por: Kotlyarov, Stanislav, et al.
Publicado: (2023)

Krüppel-Like Factors 4 and 5: Unity in Diversity
por: Sur, Inderpreet
Publicado: (2009)

The Role of Krüppel-like Factor 4 in Renal Fibrosis
por: Ke, Ben, et al.
Publicado: (2015)

The Expression and Role of Krüppel-Like Factor 4 in Psoriasis
por: Kim, Kwang Joong, et al.
Publicado: (2014)

Krüppel-like Factors 4 and 5 in Colorectal Tumorigenesis
por: Lee, Esther, et al.
Publicado: (2023)

Krüppel-like transcription factors and control of pluripotency
por: Bourillot, Pierre-Yves, et al.
Publicado: (2010)

Krüppel-like factors: Three fingers in control
por: Swamynathan, Shivalingappa K
Publicado: (2010)

Sp1- and Krüppel-like transcription factors
por: Kaczynski, Joanna, et al.
Publicado: (2003)

Kruppel-like Factors in Skeletal Physiology and Pathologies
por: Abe, Makoto, et al.
Publicado: (2022)

The Involvement of Krüppel-like Factors in Cardiovascular Diseases
por: Santoyo-Suarez, Michelle G., et al.
Publicado: (2023)

Bispidine-Amino Acid Conjugates Act as a Novel Scaffold for the Design of Antivirals That Block Japanese Encephalitis Virus Replication
por: Haridas, V., et al.
Publicado: (2013)

Corrigendum: The Role of Krüppel-like Factor 4 in Renal Fibrosis
por: Ke, Ben, et al.
Publicado: (2016)

Microglial activation induces neuronal death in Chandipura virus infection
por: Verma, Abhishek Kumar, et al.
Publicado: (2016)

Current knowledge of Krüppel-like factor 5 and vascular remodeling: providing insights for therapeutic strategies
por: Xie, Ziyan, et al.
Publicado: (2021)

Deletion of Krüppel-like factor-4 promotes axonal regeneration in mammals
por: Xu, Jin-Hui, et al.
Publicado: (2020)

Expression and Function of Kruppel Like-Factors (KLF) in Carcinogenesis
por: Bureau, Christophe, et al.
Publicado: (2009)

Krüppel-Like Factors in Metabolic Homeostasis and Cardiometabolic Disease
por: Oishi, Yumiko, et al.
Publicado: (2018)

Krüppel-Like Factors: Crippling and Uncrippling Metabolic Pathways
por: Pollak, Nina M., et al.
Publicado: (2018)

Roles of Krüppel‐like factor 5 in kidney disease
por: Li, Jia, et al.
Publicado: (2021)

The Role of Krüppel-like Factors in Pancreatic Physiology and Pathophysiology
por: Giarrizzo, Michael, et al.
Publicado: (2023)

The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration
por: Galvao, Joana, et al.
Publicado: (2018)

Kruppel-Like Factor 4 (KLF4) and its Regulation on Mitochondrial Homeostasis
por: Tung, Brian, et al.
Publicado: (2018)

Abrogation of type-I interferon signalling alters the microglial response to Aβ(1–42)
por: Moore, Zachery, et al.
Publicado: (2020)

MircoRNA-145 promotes activation of hepatic stellate cells via targeting krüppel-like factor 4
por: Men, Ruoting, et al.
Publicado: (2017)

Krüppel-like Factor 4 Regulates Intestinal Epithelial Cell Morphology and Polarity
por: Yu, Tianxin, et al.
Publicado: (2012)

Elevated Krüppel-like factor 4 transcription factor in canine mammary carcinoma
por: Chu, Pei-Yi, et al.
Publicado: (2011)

Krüppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts
por: El-Karim, Enas A, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_nrpul5idvmsbj70im5i4jiorqt