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A new essential protein discovery method based on the integration of protein-protein interaction and gene expression data

BACKGROUND: Identification of essential proteins is always a challenging task since it requires experimental approaches that are time-consuming and laborious. With the advances in high throughput technologies, a large number of protein-protein interactions are available, which have produced unpreced...

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Detalles Bibliográficos
Autores principales: Li, Min, Zhang, Hanhui, Wang, Jian-xin, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325894/
https://www.ncbi.nlm.nih.gov/pubmed/22405054
http://dx.doi.org/10.1186/1752-0509-6-15