Cargando…
GCS overexpression is associated with multidrug resistance of human HCT-8 colon cancer cells
PURPOSE: Multidrug resistance is one of the main impediments to the successful treatment of colon cancer. Glucosylceramide synthase (GCS) which is related to multidrug resistance (MDR) can reduce the level of ceramide and can help cells escape from the ceramide-induced cell apoptosis. However, the u...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325898/ https://www.ncbi.nlm.nih.gov/pubmed/22424291 http://dx.doi.org/10.1186/1756-9966-31-23 |