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GCS overexpression is associated with multidrug resistance of human HCT-8 colon cancer cells

PURPOSE: Multidrug resistance is one of the main impediments to the successful treatment of colon cancer. Glucosylceramide synthase (GCS) which is related to multidrug resistance (MDR) can reduce the level of ceramide and can help cells escape from the ceramide-induced cell apoptosis. However, the u...

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Detalles Bibliográficos
Autores principales:	Song, Min, Zang, Weidong, Zhang, Baohua, Cao, Jing, Yang, Guanrui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325898/ https://www.ncbi.nlm.nih.gov/pubmed/22424291 http://dx.doi.org/10.1186/1756-9966-31-23

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