Tibial Loading Increases Osteogenic Gene Expression and Cortical Bone Volume in Mature and Middle-Aged Mice

There are conflicting data on whether age reduces the response of the skeleton to mechanical stimuli. We examined this question in female BALB/c mice of different ages, ranging from young to middle-aged (2, 4, 7, 12 months). We first assessed markers of bone turnover in control (non-loaded) mice. Se...

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Detalles Bibliográficos
Autores principales: Silva, Matthew J., Brodt, Michael D., Lynch, Michelle A., Stephens, Abby L., Wood, Daniel J., Civitelli, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325918/
https://www.ncbi.nlm.nih.gov/pubmed/22514696
http://dx.doi.org/10.1371/journal.pone.0034980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325918/
https://www.ncbi.nlm.nih.gov/pubmed/22514696
http://dx.doi.org/10.1371/journal.pone.0034980

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