Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

Mitochondria are best known as the essential intracellular organelles that host the homeostasis required for cellular survival, but they also have relevance in diverse disease-related conditions, including Alzheimer's disease (AD). Amyloid β (Aβ) peptide is the key molecule in AD pathogenesis,...

Descripción completa

Detalles Bibliográficos
Autores principales: Cha, Moon-Yong, Han, Sun-Ho, Son, Sung Min, Hong, Hyun-Seok, Choi, Young-Ju, Byun, Jayoung, Mook-Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325919/
https://www.ncbi.nlm.nih.gov/pubmed/22514691
http://dx.doi.org/10.1371/journal.pone.0034929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325919/
https://www.ncbi.nlm.nih.gov/pubmed/22514691
http://dx.doi.org/10.1371/journal.pone.0034929

Ejemplares similares