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An Anillin-Ect2 Complex Stabilizes Central Spindle Microtubules at the Cortex during Cytokinesis

Cytokinesis occurs due to the RhoA-dependent ingression of an actomyosin ring. During anaphase, the Rho GEF (guanine nucleotide exchange factor) Ect2 is recruited to the central spindle via its interaction with MgcRacGAP/Cyk-4, and activates RhoA in the central plane of the cell. Ect2 also localizes...

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Detalles Bibliográficos
Autores principales: Frenette, Paul, Haines, Eric, Loloyan, Michael, Kinal, Mena, Pakarian, Paknoosh, Piekny, Alisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325936/
https://www.ncbi.nlm.nih.gov/pubmed/22514687
http://dx.doi.org/10.1371/journal.pone.0034888