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Activity of Clinically Relevant Antimalarial Drugs on Plasmodium falciparum Mature Gametocytes in an ATP Bioluminescence “Transmission Blocking” Assay

BACKGROUND: Current anti-malarial drugs have been selected on the basis of their activity against the symptom-causing asexual blood stage of the parasite. Which of these drugs also target gametocytes, in the sexual stage responsible for disease transmission, remains unknown. Blocking transmission is...

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Detalles Bibliográficos
Autores principales: Lelièvre, Joël, Almela, Maria Jesus, Lozano, Sonia, Miguel, Celia, Franco, Virginia, Leroy, Didier, Herreros, Esperanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325938/
https://www.ncbi.nlm.nih.gov/pubmed/22514702
http://dx.doi.org/10.1371/journal.pone.0035019