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Molecular Etiology of Atherogenesis – In Vitro Induction of Lipidosis in Macrophages with a New LDL Model

BACKGROUND: Atherosclerosis starts by lipid accumulation in the arterial intima and progresses into a chronic vascular inflammatory disease. A major atherogenic process is the formation of lipid-loaded macrophages in which a breakdown of the endolysomal pathway results in irreversible accumulation o...

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Detalles Bibliográficos
Autores principales: Estronca, Luis M. B. B., Silva, Joao C. P., Sampaio, Julio L., Shevchenko, Andrej, Verkade, Paul, Vaz, Alfin D. N., Vaz, Winchil L. C., Vieira, Otilia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325953/
https://www.ncbi.nlm.nih.gov/pubmed/22514671
http://dx.doi.org/10.1371/journal.pone.0034822