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Highly Efficient Amplification of Chronic Wasting Disease Agent by Protein Misfolding Cyclic Amplification with Beads (PMCAb)

Protein misfolding cyclic amplification (PMCA) has emerged as an important technique for detecting low levels of pathogenic prion protein in biological samples. The method exploits the ability of the pathogenic prion protein to convert the normal prion protein to a proteinase K-resistant conformatio...

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Detalles Bibliográficos
Autores principales: Johnson, Chad J., Aiken, Judd M., McKenzie, Debbie, Samuel, Michael D., Pedersen, Joel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325955/
https://www.ncbi.nlm.nih.gov/pubmed/22514738
http://dx.doi.org/10.1371/journal.pone.0035383