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Loop Diuretics Have Anxiolytic Effects in Rat Models of Conditioned Anxiety

A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties. These drugs also modulate GABA(A) mediated signalling through their antagonism of cati...

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Detalles Bibliográficos
Autores principales: Krystal, Andrew D., Sutherland, Janice, Hochman, Daryl W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325958/
https://www.ncbi.nlm.nih.gov/pubmed/22514741
http://dx.doi.org/10.1371/journal.pone.0035417