Oxidation of HMGB1 Causes Attenuation of Its Pro-Inflammatory Activity and Occurs during Liver Ischemia and Reperfusion

High mobility group box 1 (HMGB1) is a nuclear transcription factor. Once HMGB1 is released by damaged cells or activated immune cells, it acts as danger molecule and triggers the inflammatory signaling cascade. Currently, evidence is accumulating that posttranslational modifications such as oxidati...

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Detalles Bibliográficos
Autores principales: Liu, Anding, Fang, Haoshu, Dirsch, Olaf, Jin, Hao, Dahmen, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325960/
https://www.ncbi.nlm.nih.gov/pubmed/22514737
http://dx.doi.org/10.1371/journal.pone.0035379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325960/
https://www.ncbi.nlm.nih.gov/pubmed/22514737
http://dx.doi.org/10.1371/journal.pone.0035379

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