PHYRN: A Robust Method for Phylogenetic Analysis of Highly Divergent Sequences

Both multiple sequence alignment and phylogenetic analysis are problematic in the “twilight zone” of sequence similarity (≤25% amino acid identity). Herein we explore the accuracy of phylogenetic inference at extreme sequence divergence using a variety of simulated data sets. We evaluate four leadin...

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Detalles Bibliográficos
Autores principales: Bhardwaj, Gaurav, Ko, Kyung Dae, Hong, Yoojin, Zhang, Zhenhai, Ho, Ngai Lam, Chintapalli, Sree V., Kline, Lindsay A., Gotlin, Matthew, Hartranft, David Nicholas, Patterson, Morgen E., Dave, Foram, Smith, Evan J., Holmes, Edward C., Patterson, Randen L., van Rossum, Damian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325999/
https://www.ncbi.nlm.nih.gov/pubmed/22514627
http://dx.doi.org/10.1371/journal.pone.0034261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325999/
https://www.ncbi.nlm.nih.gov/pubmed/22514627
http://dx.doi.org/10.1371/journal.pone.0034261

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