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Negative Regulation of EGFR/MAPK Pathway by Pumilio in Drosophila melanogaster
In Drosophila melanogaster, specification of wing vein cells and sensory organ precursor (SOP) cells, which later give rise to a bristle, requires EGFR signaling. Here, we show that Pumilio (Pum), an RNA-binding translational repressor, negatively regulates EGFR signaling in wing vein and bristle de...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326002/ https://www.ncbi.nlm.nih.gov/pubmed/22514614 http://dx.doi.org/10.1371/journal.pone.0034016 |