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Negative Regulation of EGFR/MAPK Pathway by Pumilio in Drosophila melanogaster

In Drosophila melanogaster, specification of wing vein cells and sensory organ precursor (SOP) cells, which later give rise to a bristle, requires EGFR signaling. Here, we show that Pumilio (Pum), an RNA-binding translational repressor, negatively regulates EGFR signaling in wing vein and bristle de...

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Detalles Bibliográficos
Autores principales: Kim, Sung Yun, Kim, Ji Young, Malik, Sumira, Son, Wonseok, Kwon, Ki-Sun, Kim, Changsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326002/
https://www.ncbi.nlm.nih.gov/pubmed/22514614
http://dx.doi.org/10.1371/journal.pone.0034016