Role of Misfolded N-CoR Mediated Transcriptional Deregulation of Flt3 in Acute Monocytic Leukemia (AML)-M5 Subtype

The nuclear receptor co-repressor (N-CoR) is a key component of the generic multi-protein complex involved in transcriptional control. Flt3, a key regulator of hematopoietic cell growth, is frequently deregulated in AML (acute myeloid leukemia). Here, we report that loss of N-CoR-mediated transcript...

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Detalles Bibliográficos
Autores principales: Nin, Dawn Sijin, Kok, Wai Kay, Li, Feng, Takahashi, Shinichiro, Chng, Wee Joo, Khan, Matiullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326026/
https://www.ncbi.nlm.nih.gov/pubmed/22514634
http://dx.doi.org/10.1371/journal.pone.0034501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326026/
https://www.ncbi.nlm.nih.gov/pubmed/22514634
http://dx.doi.org/10.1371/journal.pone.0034501

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