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An Essential Regulatory Role of Downstream of Kinase-1 in the Ovalbumin-Induced Murine Model of Asthma

The downstream of kinase (DOK)-1 is involved in the protein tyrosine kinase (PTK) pathway in mast cells, but the role of DOK-1 in the pathogenesis of asthma has not been defined. In this study, we have demonstrated a novel regulatory role of DOK-1 in airway inflammation and physiologic responses in...

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Detalles Bibliográficos
Autores principales: Lee, Chang-Min, Jung, In Duk, Noh, Kyung Tae, Lee, Jun Sik, Park, Jin Wook, Heo, Deok Rim, Park, Jun Ho, Chang, Jeong Hyun, Choi, Il-Whan, Kim, Jong-Suk, Shin, Yong Kyoo, Park, Sung-Joo, Han, Myung-Kwan, Lee, Chun Geun, Cho, Won-Kyung, Park, Yeong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326039/
https://www.ncbi.nlm.nih.gov/pubmed/22514638
http://dx.doi.org/10.1371/journal.pone.0034554