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Effective DNA/RNA Co-Extraction for Analysis of MicroRNAs, mRNAs, and Genomic DNA from Formalin-Fixed Paraffin-Embedded Specimens

BACKGROUND: Retrospective studies of archived human specimens, with known clinical follow-up, are used to identify predictive and prognostic molecular markers of disease. Due to biochemical differences, however, formalin-fixed paraffin-embedded (FFPE) DNA and RNA have generally been extracted separa...

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Detalles Bibliográficos
Autores principales: Kotorashvili, Adam, Ramnauth, Andrew, Liu, Christina, Lin, Juan, Ye, Kenny, Kim, Ryung, Hazan, Rachel, Rohan, Thomas, Fineberg, Susan, Loudig, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326040/
https://www.ncbi.nlm.nih.gov/pubmed/22514653
http://dx.doi.org/10.1371/journal.pone.0034683