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Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction

Aging is marked by a decline in LV diastolic function, which encompasses abnormalities in diastolic relaxation, chamber filling and/or passive myocardial stiffness. Genetic tractability and short life span make Drosophila melanogaster an ideal organism to study the effects of aging on heart function...

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Detalles Bibliográficos
Autores principales: Kaushik, Gaurav, Zambon, Alexander C, Fuhrmann, Alexander, Bernstein, Sanford I, Bodmer, Rolf, Engler, Adam J, Cammarato, Anthony, Mercola, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326184/
https://www.ncbi.nlm.nih.gov/pubmed/22225769
http://dx.doi.org/10.1111/j.1582-4934.2011.01517.x