Disruption of TNFα/TNFR1 function in resident skin cells impairs host immune response against cutaneous vaccinia virus infection

One strategy adopted by vaccinia virus (VV) to evade the host immune system is to encode homologs of TNF receptors (TNFR) that block TNFα function. The response to VV skin infection under conditions of TNFα deficiency, however, has not been reported. We found that TNFR1−/− mice developed larger prim...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Dubin, Krista, Jin, Qiushuang, Qureshi, Ali, King, Sandra L., Liu, Luzheng, Jiang, Xiaodong, Murphy, George F., Kupper, Thomas S., Fuhlbrigge, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326195/
https://www.ncbi.nlm.nih.gov/pubmed/22318381
http://dx.doi.org/10.1038/jid.2011.489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326195/
https://www.ncbi.nlm.nih.gov/pubmed/22318381
http://dx.doi.org/10.1038/jid.2011.489

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