Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure

Retinoic acid decreases proteinuria and glomerulosclerosis in several animal models of kidney disease by protecting podocytes from injury. Our recent in vitro studies suggest that all-trans retinoic acid induces podocyte differentiation by activating the retinoic acid receptor-α (RARα)/cAMP/PKA/CREB...

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Detalles Bibliográficos
Autores principales: Zhong, Yifei, Wu, Yingwei, Liu, Ruijie, Deng, Yueyi, Mallipattu, Sandeep, Klotman, Paul, Chuang, Peter, He, John Cijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326224/
https://www.ncbi.nlm.nih.gov/pubmed/22258322
http://dx.doi.org/10.1038/ki.2011.467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326224/
https://www.ncbi.nlm.nih.gov/pubmed/22258322
http://dx.doi.org/10.1038/ki.2011.467

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