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Structural insights into the Cdt1-mediated MCM2–7 chromatin loading

Initiation of DNA replication in eukaryotes is exquisitely regulated to ensure that DNA replication occurs exactly once in each cell division. A conserved and essential step for the initiation of eukaryotic DNA replication is the loading of the mini-chromosome maintenance 2–7 (MCM2–7) helicase onto...

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Detalles Bibliográficos
Autores principales: Liu, Changdong, Wu, Rentian, Zhou, Bo, Wang, Jiafeng, Wei, Zhun, Tye, Bik K., Liang, Chun, Zhu, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326298/
https://www.ncbi.nlm.nih.gov/pubmed/22140117
http://dx.doi.org/10.1093/nar/gkr1118