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HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells
Epigenetic regulation of gene expression is important in maintaining self-renewal of embryonic stem (ES) and trophoblast stem (TS) cells. Histone deacetylases (HDACs) negatively control histone acetylation by removing covalent acetylation marks from histone tails. Because histone acetylation is a kn...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326306/ https://www.ncbi.nlm.nih.gov/pubmed/22156375 http://dx.doi.org/10.1093/nar/gkr1151 |