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Functional binding of hexanucleotides to 3C protease of hepatitis A virus

Oligonucleotides as short as 6 nt in length have been shown to bind specifically and tightly to proteins and affect their biological function. Yet, sparse structural data are available for corresponding complexes. Employing a recently developed hexanucleotide array, we identified hexadeoxyribonucleo...

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Detalles Bibliográficos
Autores principales: Blaum, Bärbel S., Wünsche, Winfried, Benie, Andrew J., Kusov, Yuri, Peters, Hannelore, Gauss-Müller, Verena, Peters, Thomas, Sczakiel, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326307/
https://www.ncbi.nlm.nih.gov/pubmed/22156376
http://dx.doi.org/10.1093/nar/gkr1152