Cargando…

2A peptides provide distinct solutions to driving stop-carry on translational recoding

Expression of viral proteins frequently includes non-canonical decoding events (‘recoding’) during translation. ‘2A’ oligopeptides drive one such event, termed ‘stop-carry on’ recoding. Nascent 2A peptides interact with the ribosomal exit tunnel to dictate an unusual stop codon-independent terminati...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Pamila, Yan, Fu, Doronina, Victoria A., Escuin-Ordinas, Helena, Ryan, Martin D., Brown, Jeremy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326317/
https://www.ncbi.nlm.nih.gov/pubmed/22140113
http://dx.doi.org/10.1093/nar/gkr1176