Cargando…
2A peptides provide distinct solutions to driving stop-carry on translational recoding
Expression of viral proteins frequently includes non-canonical decoding events (‘recoding’) during translation. ‘2A’ oligopeptides drive one such event, termed ‘stop-carry on’ recoding. Nascent 2A peptides interact with the ribosomal exit tunnel to dictate an unusual stop codon-independent terminati...
Autores principales: | Sharma, Pamila, Yan, Fu, Doronina, Victoria A., Escuin-Ordinas, Helena, Ryan, Martin D., Brown, Jeremy D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326317/ https://www.ncbi.nlm.nih.gov/pubmed/22140113 http://dx.doi.org/10.1093/nar/gkr1176 |
Ejemplares similares
-
Novel structural determinants in human SECIS elements modulate the translational recoding of UGA as selenocysteine
por: Latrèche, Lynda, et al.
Publicado: (2009) -
APE-Type Non-LTR Retrotransposons of Multicellular Organisms Encode Virus-Like 2A Oligopeptide Sequences, Which Mediate Translational Recoding during Protein Synthesis
por: Odon, Valerie, et al.
Publicado: (2013) -
Harnessing human ADAR2 for RNA repair – Recoding a PINK1 mutation rescues mitophagy
por: Wettengel, Jacqueline, et al.
Publicado: (2017) -
Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes
por: Borges, Adair L., et al.
Publicado: (2022) -
Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions
por: Vojtech, Lucia, et al.
Publicado: (2014)