Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5

An AUG in an optimal nucleotide context is the preferred translation initiation site in eukaryotic cells. Interactions among translation initiation factors, including eIF1 and eIF5, govern start codon selection. Experiments described here showed that high intracellular eIF5 levels reduced the string...

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Detalles Bibliográficos
Autores principales: Loughran, Gary, Sachs, Matthew S., Atkins, John F., Ivanov, Ivaylo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326321/
https://www.ncbi.nlm.nih.gov/pubmed/22156057
http://dx.doi.org/10.1093/nar/gkr1192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326321/
https://www.ncbi.nlm.nih.gov/pubmed/22156057
http://dx.doi.org/10.1093/nar/gkr1192

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