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Use of ChIP-Seq data for the design of a multiple promoter-alignment method

We address the challenge of regulatory sequence alignment with a new method, Pro-Coffee, a multiple aligner specifically designed for homologous promoter regions. Pro-Coffee uses a dinucleotide substitution matrix estimated on alignments of functional binding sites from TRANSFAC. We designed a valid...

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Detalles Bibliográficos
Autores principales: Erb, Ionas, González-Vallinas, Juan R., Bussotti, Giovanni, Blanco, Enrique, Eyras, Eduardo, Notredame, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326335/
https://www.ncbi.nlm.nih.gov/pubmed/22230796
http://dx.doi.org/10.1093/nar/gkr1292