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Transactivation in Drosophila of Human Enhancers by Human Transcription Factors Involved in Congenital Heart Diseases

Background: The human transcription factors (TFs) GATA4, NKX2.5 and TBX5 form part of the core network necessary to build a human heart and are involved in Congenital Heart Diseases (CHDs). The human natriuretic peptide precursor A (NPPA) and α-myosin heavy chain 6 (MYH6) genes are downstream effect...

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Detalles Bibliográficos
Autores principales: Amodio, Vincenzo, Tevy, Maria Florencia, Traina, Concetta, Ghosh, Tushar Kanti, Capovilla, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-Liss, Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326377/
https://www.ncbi.nlm.nih.gov/pubmed/21990232
http://dx.doi.org/10.1002/dvdy.22763