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Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles

INTRODUCTION: Triple-negative breast cancers (TNBCs) are characterised by lack of expression of hormone receptors and epidermal growth factor receptor 2 (HER-2). As they frequently express epidermal growth factor receptors (EGFRs), anti-EGFR therapies are currently assessed for this breast cancer su...

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Detalles Bibliográficos
Autores principales: Jacot, William, Lopez-Crapez, Evelyne, Thezenas, Simon, Senal, Romain, Fina, Frédéric, Bibeau, Frédéric, Romieu, Gilles, Lamy, Pierre-Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326575/
https://www.ncbi.nlm.nih.gov/pubmed/22192147
http://dx.doi.org/10.1186/bcr3079